About Large Volume Injection

The introduction of larger sample volumes is an attractive approach to improve the detection limits in capillary gas chromatography. The use of large volume injection can greatly improve the sensitivity of an analytical measurement. This, however, is not the only advantage of the use of large volume injection. Large volume injection can also be used as an alternative for an intermediate evaporative preconcentration step in an extraction procedure of a complex sample. This will give an big reduction in sample preparation and sample handling. Also less sample is needed, resulting in big logistic changes (smaller sampler are needed).

Large volume liquid sampling:.
Sample volume 1000ml 10ml 10ml
Elution volume 2ml 2ml 200µl
Mass in 1µl 5pg 0.05pg 0.5pg
Injection volume 1µl 100µl 100µl
Mass injected 5pg 5pg 50pg

The OPTIC-4 can be used in different LVI modes:
   - Multiple injection
   - Direct or ’at-once’ injection
   - Speed controlled sample introduction
   - Multiple ’at-once’ injection
   - PTV on-column injection








OPTIC-4 Multimode Inlet












  OPTIC-4
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